Accueil LBFA BEeSy Inserm Université de Grenoble
Le Laboratoire



Gestion des Pôles


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Liens utiles




UFR associées

Thèses soutenues








• 2008

Simonneau G, Rubin LJ, Galiè N, Barst RJ, Fleming TR, Frost AE, Engel PJ, Kramer MR, Burgess G, Collings L, Cossons N, Sitbon O, Badesch DB, Pison C ; PACES Study Group. Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial. Ann Intern Med. 2008 Oct 21;149(8):521-30. Erratum in: Ann Intern Med. 2009;150(1):63. Summary for patients in: Ann Intern Med. 2008;149(8):I-38.

Pironi L, Forbes A, Joly F, Colomb V, Lyszkowska M, Van Gossum A, Baxter J, Thul P, Hébuterne X, Gambarara M, Gottrand F, Moreno Villares JM, Messing B, Goulet O, Staun M, Fontaine E ; Home Artificial Nutrition Working Group of the European Society for Clinical Nutrition and Metabolism (ESPEN). Survival of patients identified as candidates for intestinal transplantation: a 3-year prospective follow-up. Gastroenterology. 2008l;135(1):61-71.

Rostovtseva TK, Sheldon KL, Hassanzadeh E, Monge C, Saks V, Bezrukov SM, Sackett DL. Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration. Proc Natl Acad Sci U S A. 2008;105(48):18746-51.

Polge C, Jossier M, Crozet P, Gissot L, Thomas M. Beta-subunits of the SnRK1 complexes share a common ancestral function together with expression and function specificities; physical interaction with nitrate reductase specifically occurs via AKINbeta1-subunit. Plant Physiol. 2008;148(3):1570-82.

Leverve X. To cope with oxygen: a long and still tumultuous story for life. Crit Care Med. 2008;36(2):637-8.

Tokarska-Schlattner M, Boissan M, Munier A, Borot C, Mailleau C, Speer O, Schlattner U, Lacombe ML. The nucleoside diphosphate kinase D (NM23-H4) binds the inner mitochondrial membrane with high affinity to cardiolipin and couples nucleotide transfer with respiration. J Biol Chem. 2008;283(38):26198-207.

Riek U, Scholz R, Konarev P, Rufer A, Suter M, Nazabal A, Ringler P, Chami M, Müller SA, Neumann D, Forstner M, Hennig M, Zenobi R, Engel A, Svergun D, Schlattner U, Wallimann T. Structural properties of AMP-activated protein kinase: dimerization, molecular shape, and changes upon ligand binding. J Biol Chem. 2008;283(26):18331-43.

Bogenhagen DF, Rousseau D, Burke S. The layered structure of human mitochondrial DNA nucleoids. J Biol Chem. 2008;283(6):3665-75.

Roche N, Zureik M, Soussan D, Neukirch F, Perrotin D, Pison C; Urgence BPCO (COPD Emergency) Scientific Committee. Predictors of outcomes in COPD exacerbation cases presenting to the emergency department. Eur Respir J. 2008;32:953-61.

Arnaud J, Weber JP, Weykamp CW, Parsons PJ, Angerer J, Mairiaux E, Mazarrasa O, Valkonen S, Menditto A, Patriarca M, Taylor A. Quality specifications for the determination of copper, zinc, and selenium in human serum or plasma: evaluation of an approach based on biological and analytical variation. Clin Chem. 2008;54(11):1892-9.

Leverve X, Boon C, Hakim T, Anwar M, Siregar E, Mustafa I. Half-molar sodium-lactate solution has a beneficial effect in patients after coronary artery bypass grafting. Intensive Care Med. 2008;34(10):1796-803.

Saks V. The phosphocreatine-creatine kinase system helps to shape muscle cells and keep them healthy and alive. J Physiol. 2008;586(Pt 12):2817-8.

Romestaing C, Piquet MA, Letexier D, Rey B, Mourier A, Servais S, Belouze M, Rouleau V, Dautresme M, Ollivier I, Favier R, Rigoulet M, Duchamp C, Sibille B. Mitochondrial adaptations to steatohepatitis induced by a methionine- and choline-deficient diet. Am J Physiol Endocrinol Metab. 2008;294(1):E110-9.

Eimre M, Paju K, Pelloux S, Beraud N, Roosimaa M, Kadaja L, Gruno M, Peet N, Orlova E, Remmelkoor R, Piirsoo A, Saks V, Seppet E. Distinct organization of energy metabolism in HL-1 cardiac cell line and cardiomyocytes. Biochim Biophys Acta. 2008;1777(6):514-24.

Hubstenberger A, Labourdette G, Baudier J, Rousseau D. ATAD 3A and ATAD 3B are distal 1p-located genes differentially expressed in human glioma cell lines and present in vitro anti-oncogenic and chemoresistant properties. Exp Cell Res. 2008;314(15):2870-83.

Lacraz G, Couturier K, Taleux N, Servais S, Sibille B, Letexier D, Guigas B, Dubouchaud H, Leverve X, Favier R. Liver mitochondrial properties from the obesity-resistant Lou/C rat. Int J Obes (Lond). 2008;32(4):629-38.

Taleux N, De Potter I, Deransart C, Lacraz G, Favier R, Leverve XM, Hue L, Guigas B. Lack of starvation-induced activation of AMP-activated protein kinase in the hypothalamus of the Lou/C rats resistant to obesity. Int J Obes (Lond). 2008;32(4):639-47.

Patra S, Bera S, SinhaRoy S, Ghoshal S, Ray S, Basu A, Schlattner U, Wallimann T, Ray M. Progressive decrease of phosphocreatine, creatine and creatine kinase in skeletal muscle upon transformation to sarcoma. FEBS J. 2008;275(12):3236-47.

Pogoryelov D, Nikolaev Y, Schlattner U, Pervushin K, Meier T, Dimroth P. Probing the rotor subunit interface of the ATP synthase from Ilyobacter tartaricus. FEBS J. 2008;275:4850-62.

Brugière O, Thabut G, Suberbielle C, Reynaud-Gaubert M, Thomas P, Pison C, Saint Raymond C, Mornex JF, Bertocchi M, Dromer C, Velly JF, Stern M, Philippe B, Dauriat G, Biondi G, Castier Y, Fournier M. Relative impact of human leukocyte antigen mismatching and graft ischemic time after lung transplantation. J Heart Lung Transplant. 2008;27(6):628-34.

Cano NJ, Leverve XM. Intradialytic nutritional support. Curr Opin Clin Nutr Metab Care. 2008;11(2):147-51.

Aniwidyaningsih W, Varraso R, Cano N, Pison C. Impact of nutritional status on body functioning in chronic obstructive pulmonary disease and how to intervene. Curr Opin Clin Nutr Metab Care. 2008;11(4):435-42. Review.

Riek U, Tuerk R, Wallimann T, Schlattner U, Neumann D. An automated home-built low-cost fermenter suitable for large-scale bacterial expression of proteins in Escherichia coli. Biotechniques. 2008;45(2):187-9.

Guiraud A, de Lorgeril M, Zeghichi S, Laporte F, Salen P, Saks V, Beraud N, Boucher F, de Leiris J. Interactions of ethanol drinking with n-3 fatty acids in rats: potential consequences for the cardiovascular system. Br J Nutr. 2008;100(6):1237-44.

Astorg P, Bertrais S, Laporte F, Arnault N, Estaquio C, Galan P, Favier A, Hercberg S. Plasma n-6 and n-3 polyunsaturated fatty acids as biomarkers of their dietary intakes: a cross-sectional study within a cohort of middle-aged French men and women. Eur J Clin Nutr. 2008 Oct;62(10):1155-61.

Intorre F, Polito A, Andriollo-Sanchez M, Azzini E, Raguzzini A, Toti E, Zaccaria M, Catasta G, Meunier N, Ducros V, O'Connor JM, Coudray C, Roussel AM, Maiani G. Effect of zinc supplementation on vitamin status of middle-aged and older European adults: the ZENITH study. Eur J Clin Nutr. 2008;62(10):1215-23.

Andriollo-Sanchez M, Hininger-Favier I, Meunier N, Venneria E, O'Connor JM, Maiani G, Polito A, Bord S, Ferry M, Coudray C, Roussel AM. No antioxidant beneficial effect of zinc supplementation on oxidative stress markers and antioxidant defenses in middle-aged and elderly subjects: the Zenith study. J Am Coll Nutr. 2008;27(4):463-9.

Detaille D, Sanchez C, Sanz N, Lopez-Novoa JM, Leverve X, El-Mir MY. Interrelation between the inhibition of glycolytic flux by silibinin and the lowering of mitochondrial ROS production in perifused rat hepatocytes. Life Sci. 2008;82(21-22):1070-6.

Carpentier YA, Peltier S, Portois L, Sebedio JL, Leverve X, Malaisse WJ. Rapid reduction of liver steatosis in omega3-depleted rats injected with a novel lipid emulsion. Horm Metab Res. 2008;40(12):875-9.

Borel AL, Boizel R, Faure P, Barbe G, Boutonnat J, Sturm N, Seigneurin D, Bricault I, Caravel JP, Chaffanjon P, Chabre O. Significance of low levels of thyroglobulin in fine needle aspirates from cervical lymph nodes of patients with a history of differentiated thyroid cancer. Eur J Endocrinol. 2008;158(5):691-8.

Flore P, Bricout VA, van Biesen D, Guinot M, Laporte F, Pépin JL, Eberhard Y, Favre-Juvin A, Wuyam B, van de Vliet P, Faure P. Oxidative stress and metabolism at rest and during exercise in persons with Down syndrome. Eur J Cardiovasc Prev Rehabil. 2008;15(1):35-42.

Laforest L, Van Ganse E, Devouassoux G, Osman LM, Pison C, El Hasnaoui A, Bauguil G, Chamba G. Factors influencing dispensing of psychotropic medications to patients with asthma: a community pharmacy-based survey. Ann Allergy Asthma Immunol. 2008;100(3):230-6.

Bouhlel I, Valenti K, Kilani S, Skandrani I, Ben Sghaier M, Mariotte AM, Dijoux-Franca MG, Ghedira K, Hininger-Favier I, Laporte F, Chekir-Ghedira L. Antimutagenic, antigenotoxic and antioxidant activities of Acacia salicina extracts (ASE) and modulation of cell gene expression by H2O2 and ASE treatment. Toxicol In Vitro. 2008;22(5):1264-72.

Dubourdeau M, Chêne G, Coste A, Bernad J, Lepert JC, Orfila C, Pipy B, Rousseau D. Opposite roles of STAT and PPARgamma in the induction of p21WAF1 expression by IL-13 in human peripheral blood monocytes. Eur Cytokine Netw. 2008;19(4):156-65.

Agay D, Andriollo-Sanchez M, Claeyssen R, Touvard L, Denis J, Roussel AM, Chancerelle Y. Interleukin-6, TNF-alpha and interleukin-1 beta levels in blood and tissue in severely burned rats. Eur Cytokine Netw. 2008;19(1):1-7.

Andres RH, Ducray AD, Schlattner U, Wallimann T, Widmer HR. Functions and effects of creatine in the central nervous system. Brain Res Bull. 2008;76(4):329-43. Review.

Andriollo-Sanchez M, Claeyssen R, Arnaud J, Touvard L, Denis J, Chancerelle Y, Roussel AM, Agay D. Toxic effects of iterative intraperitoneal administration of zinc gluconate in rats. Basic Clin Pharmacol Toxicol. 2008;103(3):267-72.

El-Mir MY, Detaille D, R-Villanueva G, Delgado-Esteban M, Guigas B, Attia S, Fontaine E, Almeida A, Leverve X. Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons. J Mol Neurosci. 2008;34(1):77-87.

Monge C, Beraud N, Kuznetsov AV, Rostovtseva T, Sackett D, Schlattner U, Vendelin M, Saks VA. Regulation of respiration in brain mitochondria and synaptosomes: restrictions of ADP diffusion in situ, roles of tubulin, and mitochondrial creatine kinase. Mol Cell Biochem. 2008;318(1-2):147-65.

Kuznetsov AV, Veksler V, Gellerich FN, Saks V, Margreiter R, Kunz WS. Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells. Nat Protoc. 2008;3(6):965-76.

Pettifor JM, Fischer PR, Thacher TD, Arnaud J, Meissner CA. Dietary calcium deficiency & rickets. Indian J Med Res. 2008;128(5):673-4; author reply 674-6.

Vial G, Dubouchaud H, Couturier K, Lanson M, Leverve X, Demaison L. Na+/H+ exchange inhibition with cariporide prevents alterations of coronary endothelial function in streptozotocin-induced diabetes. Mol Cell Biochem. 2008;310(1-2):93-102.

Craviari T, Pettifor JM, Thacher TD, Meisner C, Arnaud J, Fischer PR; Rickets Convergence Group. Rickets: an overview and future directions, with special reference to Bangladesh. A summary of the Rickets Convergence Group meeting, Dhaka, 26-27 January 2006. J Health Popul Nutr. 2008;26(1):112-21. Review.

Toffart AC, Bouvaist H, Feral V, Blin D, Pison C. Hypoxemia-orthodeoxia related to patent foramen ovale without pulmonary hypertension. Heart Lung. 2008;37(5):385-9.

Claeyssen R, Andriollo-Sanchez M, Arnaud J, Touvard L, Alonso A, Chancerelle Y, Roussel AM, Agay D. Burn-induced oxidative stress is altered by a low zinc status: kinetic study in burned rats fed a low zinc diet. Biol Trace Elem Res. 2008;126 Suppl 1:S80-96.

Saks V, Beraud N, Wallimann T. Metabolic compartmentation - a system level property of muscle cells: real problems of diffusion in living cells. Int J Mol Sci. 2008;9(5):751-67.

Bouhlel I, Kilani S, Skandrani I, Ben Amar R, Nefatti A, Laporte F, Hininger-Favier I, Ghedira K, Chekir-Ghedira L. Acacia salicina extracts protect against DNA damage and mutagenesis in bacteria and human lymphoblast cell K562 cultures. Nutr Res. 2008;28(3):190-7.

Hohn N, Salameire D, Pison C, Dubois C, Ferretti G.[Dense spontaneous bronchogram] Rev Mal Respir. 2008;25(5):619-21.

Thabut G, Mornex JF, Cuvelier A, Padrazzi B, Pison C, Neukirch F, Lafitte JJ, Boczkowski J, Balduyck M, Muir JF, Carles P, Fournier M. [Characteristics of the patients included in the French cohort of patients with emphysema caused by alpha-1 antitrypsin deficiency] Rev Mal Respir. 2008;25(9):1115-22.

Couturaud F, Pernod G, Pison C, Mismetti P, Sanchez O, Meyer G, Parent F, Girard P, Simonneau G, Drouet L, Gueret P, Jego P, Delaval P, Duhamel E, Gruel Y, Delahousse B, Regina S, Pottier P, Connaud J, Lecomte F, Provost K, Vilmans N, Gosset X, Bura-Rivière A, Meach G, Lacut K, Bosson JL, Guillot K, Mottier D, Leroyer C. [Prolongation of anti vitamin K treatment for 18 months versus placebo after 6 months treatment of a first episode of ideopathic pulmonary embolism: a mutlicentre, randomised double blind trail. The PADIS-EP Trial] Rev Mal Respir. 2008;25(7):885-93.

Laforest L, Com-Ruelle L, Devouassoux G, Pison C, Van Ganse E. [Economic aspects of severe asthma] Presse Med. 2008;37(1 Pt 2):117-28. Review.

Siroux V, Bouzigon E, Dizier MH, Pin I, Demenais F, Kauffmann F, Pison C; EGEA cooperative group. Replication of association between ADAM33 polymorphisms and psoriasis. PLoS ONE. 2008;3(6):e2448.

Cinnamon, glucose and insulin sensitivity. In :Nutraceuticals, Glycemic Health and type 2 Diabetes. Anderson RA, Roussel AM. VK Pasupulet and JW Anderson, Editors, Wiley-Blackwell, IFT press, Ames, Iowa, USA. 2008, p 127-141.